Cord Blood Stem Cells
Umbilical cord blood stem sells are present in umbilical cord blood at birth. These stem cells Stem Cells
Undifferentiated cells,
Undifferentiated Cells
Cells that can become other cell types. They have not yet decided their fate; what type of cell they will become.
that can give rise to more mature differentiated cells and have the ability to self-replicate. There are many kinds of stem cells – adult stem cells (AS), embryonic cells (ES), embryonic germ cells (EG).
are multipotent Multipotent
Ability of a single stem cell to develop into more than one cell type of the body. See also
pluripotent.
Pluripotent Stem-Cells
Stem cells, which can develop into any of the three major tissue types: endoderm (interior gut lining), mesoderm (muscle, bone, blood), and ectoderm (epidermal tissues and nervous system). Pluripotent stem cells can eventually specialize in any bodily tissue, but they cannot themselves develop into a human being.
and more versatile than adult stem cells, Adult Stem Cells
Undifferentiated Stem cells found among
differentiated cells Differentiated Cells
Cells that have developed into a specific type, like a neuron or blood cell.
in a tissue or organ. It can renew itself and can differentiate to yield the major specialized cell types of that tissue or organ in which its found.
but do not have the same capacity to become any type of cell as do embryonic stem cells. Embryonic Stem Cells Embryonic Stem Cells
Pluripotent cells that can differentiate into various tissues in the body.
Pluripotent cells that can differentiate into various tissues in the body.
The advantage of using cord blood stem cells is that they are virtually effortless to collect and free from any risks to the baby or mother.
The disadvantage of cord blood stem cells is that there are relatively few numbers of them available in the cord blood and they do not grow as well in culture as hESCs. hESCs
Human embryonic stem cells.
This makes working with cord blood stem cells harder. Another disadvantage is that an exact genetic copy can be created with hESC, hESC
Human embryonic stem cells.
which cannot be done with umbilical cord blood stem cells, unless it is the cord blood of the patient.
Umbilical cord blood stem cell transplants are currently being used to treat leukemia and other blood disorders.